What is PhotoDynamic Therapy?
Photodynamic therapy (PDT) uses light-sensitive compounds that are exposed selectively to light, whereupon they become activated and destroy targeted diseased cells.
PDT has proven ability to kill microbial cells including bacteria, fungi and viruses.
PDT Treatment has three important components:
- a photosensitiser (eg ALA)
- a light source (eg Laser or LED, such as Blue Light); and
- tissue oxygen
The sebaceous glands and bacteria (Propionobacterium Acnes) that cause Acne are metabolically more active than normal cells, so they preferentially take up the ALA , to then produce large amounts of porphyrin.
When subsequently exposed to light (LED or Laser), a chemical reaction occurs and Oxygen Free Radicals are produced that selectively destroy the diseased cells and bacteria without damaging normal ones.
What is involved in the PDT Procedure?